Preparation:

Step 1: Prepare the Filling

1. Begin by cooking the ground beef and Italian sausage in a skillet over medium heat, stirring occasionally until both are browned and fully cooked.
2. Drain any excess fat from the skillet to avoid a greasy pie.
3. Once the meat is cooked, set it aside to cool slightly.

Step 2: Preheat the Oven

1. Meanwhile, preheat your oven to 425°F (220°C).

Step 3: Assemble the Pizza Pie

1. Roll out one of the pie crusts and gently press it into a deep-dish pie pan or an oven-safe skillet, covering the bottom and sides.
2. Spread half of the shredded mozzarella cheese evenly across the bottom of the crust.
3. Follow with an even layer of the cooked ground beef and Italian sausage mixture, pressing it gently into the cheese.
4. Add half of the pepperoni slices in an even layer over the meat.
5. Next, pour the pizza sauce over the pepperoni and meat, using a spoon to spread it evenly.
6. For extra flavor, sprinkle Italian seasoning, garlic powder, and red pepper flakes (if using) over the sauce layer.
7. Top with the remaining mozzarella cheese, then add shredded cheddar or provolone for a blend of cheesy flavors.
8. Finally, arrange the remaining pepperoni slices on top of the cheese layer.

Step 4: Add the Top Crust

1. Carefully roll out the second pie crust and place it over the filling.
2. Press the edges of both crusts together to seal, ensuring the filling stays inside.
3. Brush the top crust with melted butter and sprinkle lightly with garlic powder for extra flavor.

Step 5: Bake the Pizza Pie

1. Place the assembled pie in the preheated oven.
2. Bake for 20-25 minutes, or until the crust is golden brown and the cheese is melted and bubbly.
3. Once baked, remove the pie from the oven and let it cool for a few minutes before slicing.

Step 6: Serve

1. Slice the pie into generous portions.
2. Serve immediately, and enjoy the rich, comforting flavors of this ultimate deep-dish pizza pie!